RASSF1 anticorps

N° du produit ABIN2730552

L’anticorps Souris Monoclonal anti-RASSF1 a été validé pour WB, IF, IHC et FACS. Il convient pour détecter RASSF1 dans des échantillons de Humain.

Aperçu rapide pour RASSF1 anticorps (ABIN2730552)

Antigène: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RASSF1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 2B11

Détail du produit anti-RASSF1 anticorps

Attributs du produit: Homo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), transcript variant A

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human RASSF1 (NP_009113) produced in E.coli.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur RASSF1

Antigène: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Autre désignation: RASSF1

Sujet: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Poids moléculaire: 38.6 kDa

ID gène: 11186

NCBI Accession: NM_007182

HGNC: 28844